منابع مشابه
Transgenic Rice Expressing Amyloid β-peptide for Oral Immunization
Various vaccine therapies for Alzheimer's disease (AD) have been investigated. Here we report transgenic rice expressing amyloid β-peptide (Aβ). The Aβ42 gene fused with a green fluorescent protein gene was introduced into rice using the Agrobacterium method. When transgenic brown rice expressing Aβ was orally administered to mice, serum anti-Aβ antibody titers were elevated. The same results w...
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Objective(s):Antibodies against actin, as one of the most widely studied structural and multifunctional housekeeping proteins in eukaryotic cells, are used as internal loading controls in western blot analyses. The aim of this study was to produce polyclonal antibody against a synthetic peptide derived from N-terminal region of β-actin protein to be used as a protein loading control in western ...
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متن کاملβ-Peptide coatings by surface-initiated polymerization.
Homopolymers of β-lactams can be grown by surface-initiated polymerization. These surface-linked β-peptides are living polymers with the potential to be utilized as tunable, protease-resistant interfaces in multiphase structural composites where the characteristics of the interface influence bulk properties.
متن کاملAmyloid-β peptide promotes bacterial aging
The pathological hallmark of Alzheimer's disease is brain deposition of senile plaques composed predominantly of amyloid fibrils. These conformational structures, characteristic of many other human disorders, are formed mainly by the amyloid-β peptide Aβ42. This peptide, which is primarily disordered and soluble as an isolated monomer, can undergo an aggregation and fibrillation process that re...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2000
ISSN: 0003-9942
DOI: 10.1001/archneur.57.7.934